Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213106 | 0.88 | ADRB2 (0.54) | ADRB2 | |
| SCHEMBL2212564 | 0.86 | ADRB2 (0.56) | ADRB2ADRB1 | |
| SCHEMBL2213191 | 0.82 | ADRB2 (0.69) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL2211456 | 0.82 | ADRB2 (0.61) | ADRB2 | |
| SCHEMBL2209331 | 0.82 | ADRB2 (0.54) | ADRB2ABCB11 | |
| SCHEMBL2212095 | 0.81 | ADRB2 (0.53) | ADRB2 | |
| SCHEMBL2213120 | 0.80 | ADRB2 (0.53) | ADRB2 | |
| SCHEMBL2211462 | 0.79 | ADRB2 (0.45) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| Trifluoroacetic Acid SCHEMBL2213831 | 0.79 | ADRB2 (0.51) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2206725 | 0.79 | ADRB2 (0.64) | ADRB2ABCB11ADRB1DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121642-A1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075026-A1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |