Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451119 | 0.90 | S1PR2 (0.51) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL10345872 | 0.88 | MAOA (0.52) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL7022054 | 0.88 | MAOA (0.52) | S1PR2S1PR4S1PR1S1PR3MAOA | |
| SCHEMBL28586667 | 0.83 | SCN4A (0.47) | HTR2A | |
| SCHEMBL8631288 | 0.83 | KCNH2 (0.50) | IDO1MAOAHTR2AKCNH2MAOB | |
| SCHEMBL22456887 | 0.83 | SCN4A (0.46) | IDO1 | |
| SCHEMBL22456941 | 0.83 | SCN4A (0.46) | IDO1 | |
| SCHEMBL22456839 | 0.83 | SCN4A (0.46) | IDO1 | |
| SCHEMBL2670021 | 0.81 | S1PR2 (0.51) | TDP1L3MBTL1S1PR2S1PR4S1PR1 | |
| SCHEMBL7449325 | 0.81 | TDP1 (0.61) | TDP1L3MBTL1IDO1MAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032546-A2 | PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |