Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 19/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554105 | 0.87 | CETP (0.51) | CETP | |
| SCHEMBL3729583 | 0.84 | CETP (0.64) | CETP | |
| SCHEMBL12664974 | 0.82 | CETP (0.64) | CETP | |
| SCHEMBL9885285 | 0.80 | CETP (1.00) | CETP | |
| SCHEMBL9885316 | 0.77 | CETP (0.68) | CETP | |
| SCHEMBL9885322 | 0.75 | CETP (0.70) | CETP | |
| SCHEMBL3559178 | 0.75 | PIN1 (0.45) | CETP | |
| SCHEMBL1893336 | 0.73 | CETP (0.67) | CETP | |
| SCHEMBL3553339 | 0.73 | CETP (0.66) | CETP | |
| SCHEMBL3554050 | 0.72 | CETP (0.86) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737811-A4 | CETP INHIBITORS | MERCK & CO INC (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1737811-A1 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100298-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2005-10-27 | — | — | WO | disclosed |