SCHEMBL4566536

SCHEMBL4566536

Cn1cc(C2CN(CCF)C2)c2ccc(-n3ccc(-c4ccc(C(F)(F)F)cn4)cc3=O)cc21

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 17/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13653419 0.84 MCHR1 (0.55) MCHR1
SCHEMBL13622687 0.80 MCHR1 (0.52) MCHR1
SCHEMBL13653331 0.80 MCHR1 (0.55) MCHR1
SCHEMBL4374344 0.77 MCHR1 (0.39) MCHR1
SCHEMBL4231766 0.76 MCHR1 (0.51) MCHR1
SCHEMBL4238507 0.75 MCHR1 (0.58) MCHR1
SCHEMBL13025487 0.74 MCHR1 (0.82) MCHR1
SCHEMBL10111935 0.73 MCHR1 (1.00) MCHR1
SCHEMBL12954195 0.73 MCHR1 (0.81) MCHR1
SCHEMBL11424267 0.73 MCHR1 (0.90) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009120655-A1 INDOLE DERIVATIVES H. LUNDBECK A/S (DK) 2009-10-01 WO claimed