Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13653419 | 0.77 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL4237052 | 0.69 | MCHR1 (0.38) | MCHR1 | |
| SCHEMBL13653331 | 0.68 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL13622711 | 0.67 | MCHR1 (0.41) | MCHR1 | |
| SCHEMBL4062804 | 0.67 | MCHR1 (0.49) | MCHR1DRD2SLC6A4 | |
| SCHEMBL4565591 | 0.67 | KCNH2 (0.41) | MCHR1SLC6A4F10 | |
| SCHEMBL4231766 | 0.65 | MCHR1 (0.51) | MCHR1 | |
| SCHEMBL13622864 | 0.64 | MCHR1 (0.58) | MCHR1 | |
| SCHEMBL4238507 | 0.64 | MCHR1 (0.58) | MCHR1 | |
| SCHEMBL12059313 | 0.60 | MCHR1 (0.68) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120655-A1 | INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | WO | claimed |
| WO-2009120655-A1 | INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | WO | disclosed |