Prochloraz

Prochloraz

SCHEMBL4566549

CC(C)(O)C(=O)c1ccc(OCCO)cc1.CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n1ccnc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.70
CYP19A1 P11511 4/20 0.36
TSPO P30536 2/20 0.36
TBXAS1 P24557 7/20 0.34
ADRB2 P07550 2/20 0.34
ADRB1 P08588 2/20 0.34
ADRB3 P13945 2/20 0.34
GAA P10253 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prochloraz SCHEMBL7886151 0.90 AHR (0.74) AHRCYP19A1TSPOADRB2ADRB1
Prochloraz SCHEMBL11634975 0.85 AHR (0.94) AHRTSPOADRB2ADRB1ADRB3
Prochloraz SCHEMBL1154128 0.84 AHR (0.96) AHRADRB2ADRB1ADRB3MAPK1
Prochloraz SCHEMBL34675 0.84 AHR (1.00) AHRADRB2ADRB1ADRB3MAPK1
Prochloraz SCHEMBL22242 0.84 AHR (1.00) AHRADRB2ADRB1ADRB3MAPK1
Prochloraz SCHEMBL10901968 0.83 AHR (0.86) AHRTSPOADRB2ADRB1ADRB3
Prochloraz SCHEMBL9371936 0.83 AHR (0.98) AHRADRB2ADRB1ADRB3MAPK1
Prochloraz SCHEMBL11376171 0.83 AHR (0.98) AHRADRB2ADRB1ADRB3MAPK1
Prochloraz SCHEMBL12611119 0.83 AHR (0.98) AHRADRB2ADRB1ADRB3MAPK1
Prochloraz SCHEMBL11375792 0.83 AHR (0.98) AHRADRB2ADRB1ADRB3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112933-A1 STRAIN-HARDENED INTERPENETRATING POLYMER NETWORK HYDROGEL The Board of Trustees of The Leland Stanford Junior University (US) 2009-11-04 EP disclosed
WO-2008100617-A1 STRAIN-HARDENED INTERPENETRATING POLYMER NETWORK HYDROGEL THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-08-21 WO disclosed