Prochloraz

Prochloraz

SCHEMBL7886151

CC(C)(c1ccc(OCCO)cc1)c1ccc(OCCO)cc1.CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n1ccnc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.74
TSPO P30536 2/20 0.38
POLB P06746 2/20 0.35
KDM4E B2RXH2 2/20 0.35
ADRB2 P07550 2/20 0.35
ADRB1 P08588 2/20 0.35
ADRB3 P13945 2/20 0.35
CYP19A1 P11511 2/20 0.34
GAA P10253 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
AGTR2 P50052 1/20 0.32
THRB P10828 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prochloraz SCHEMBL4566549 0.90 AHR (0.70) AHRTSPOADRB2ADRB1ADRB3
Prochloraz SCHEMBL5493293 0.87 AHR (0.74) AHRPOLBKDM4EADRB2ADRB1
Prochloraz SCHEMBL11634975 0.87 AHR (0.94) AHRTSPOKDM4EADRB2ADRB1
Prochloraz SCHEMBL1154128 0.86 AHR (0.96) AHRKDM4EADRB2ADRB1ADRB3
Prochloraz SCHEMBL34675 0.86 AHR (1.00) AHRKDM4EADRB2ADRB1ADRB3
Prochloraz SCHEMBL22242 0.86 AHR (1.00) AHRKDM4EADRB2ADRB1ADRB3
Prochloraz SCHEMBL10901968 0.85 AHR (0.86) AHRTSPOKDM4EADRB2ADRB1
Prochloraz SCHEMBL12611119 0.85 AHR (0.98) AHRKDM4EADRB2ADRB1ADRB3
Prochloraz SCHEMBL9371936 0.85 AHR (0.98) AHRKDM4EADRB2ADRB1ADRB3
Prochloraz SCHEMBL11376171 0.85 AHR (0.98) AHRKDM4EADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177192-B1 COPOLYESTER COMPRISING ETHYLENE 2,6-NAPHTHALATE UNITS, AND DIOL COMPONENT COMPRISING ALKYLENE OXIDE ADDUCT OF A DIVALENT PHENOL; USEFUL AS A MATERIAL FOR AN INDUSTRIAL APPLICATION SUCH AS A DRYER CANVAS FOR PAPERMAKING TEIJIN LIMITED (JP) 2001-01-23 US disclosed