Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.39 |
| ▸ | KLK7 | P49862 | 5/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30428928 | 0.89 | HPGD (0.43) | HPGDFKBP1AKLK7HTR2CGAA | |
| SCHEMBL15122638 | 0.84 | HPGD (0.45) | HPGDFKBP1AHTR2CPARP1 | |
| SCHEMBL15122636 | 0.84 | HPGD (0.45) | HPGDFKBP1AHTR2CPARP1 | |
| SCHEMBL28968201 | 0.83 | HPGD (0.43) | HPGDFKBP1AHTR2CNPC1RAB9A | |
| SCHEMBL31148977 | 0.82 | HTT (0.43) | HPGDFKBP1AKLK7HTR2CNPC1 | |
| SCHEMBL14814073 | 0.79 | NPC1 (0.44) | HPGDFKBP1AHTR2CGAANPC1 | |
| SCHEMBL20701416 | 0.76 | FKBP1A (0.46) | FKBP1AHTR2C | |
| SCHEMBL20701420 | 0.76 | FKBP1A (0.46) | FKBP1AHTR2C | |
| SCHEMBL1448039 | 0.76 | HTR2C (0.48) | FKBP1AHTR2CGAANPC1MAPK1 | |
| SCHEMBL6691930 | 0.76 | HTR2C (0.48) | FKBP1AHTR2CGAANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |