SCHEMBL4567310

SCHEMBL4567310

c1ccc2c(c1)ccc1ccc3cc(-c4ccc5oc6ccc(-c7ccc8c(ccc9ccc%10ccccc%10c98)c7)cc6c5c4)ccc3c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ABCG2 Q9UNQ0 5/20 0.45
PAX8 Q06710 2/20 0.45
CYP1A2 P05177 2/20 0.45
FYN P06241 2/20 0.45
AHR P35869 2/20 0.45
CYP1A1 P04798 1/20 0.45
MAPK3 P27361 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 1/20 0.44
KDM4E B2RXH2 4/20 0.44
GLA P06280 2/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HNF4A P41235 1/20 0.43
CASP3 P42574 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12071354 0.91 KDM4E (0.51) TDP1L3MBTL1CYP1A1NPC1RAB9A
SCHEMBL17692105 0.90 KDM4E (0.47) TDP1L3MBTL1ABCG2PAX8CYP1A2
SCHEMBL4567324 0.90 KDM4E (0.50) TDP1L3MBTL1NPC1RAB9AKDM4E
SCHEMBL4567312 0.90 KDM4E (0.50) TDP1L3MBTL1NPC1RAB9AKDM4E
SCHEMBL17692106 0.89 KDM4E (0.46) TDP1L3MBTL1ABCG2PAX8CYP1A2
SCHEMBL4567313 0.86 TDP1 (0.43) TDP1L3MBTL1ABCG2PAX8CYP1A2
SCHEMBL27026482 0.85 KDM4E (0.46) TDP1L3MBTL1AHRNPC1RAB9A
SCHEMBL16417805 0.84 ABCG2 (0.41) TDP1L3MBTL1ABCG2PAX8CYP1A2
SCHEMBL4567323 0.84 HPRT1 (0.52) TDP1L3MBTL1NPC1RAB9AKDM4E
SCHEMBL12037380 0.84 TDP1 (0.39) TDP1L3MBTL1ABCG2PAX8CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120119196-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 US disclosed
US-20120119196-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 US disclosed