SCHEMBL4567323

SCHEMBL4567323

c1ccc2c(c1)ccc1c2ccc2c3ccc4ccc(-c5ccc6oc7ccc(-c8ccc9ccc%10c(ccc%11c%12ccc%13ccccc%13c%12ccc%10%11)c9c8)cc7c6c5)cc4c3ccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.52
KDM4E B2RXH2 7/20 0.51
MAPT P10636 4/20 0.51
HSD17B10 Q99714 4/20 0.51
HPGD P15428 3/20 0.51
GLA P06280 3/20 0.51
TSHR P16473 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
HNF4A P41235 1/20 0.50
ALDH1A1 P00352 9/20 0.48
HIF1A Q16665 1/20 0.48
CYP1B1 Q16678 1/20 0.48
GAA P10253 3/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA9 Q16790 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15856966 0.96 KDM4E (0.49) HPRT1KDM4EMAPTHSD17B10HPGD
SCHEMBL12070210 0.96 KDM4E (0.54) HPRT1KDM4EMAPTHSD17B10HPGD
SCHEMBL4567312 0.95 KDM4E (0.50) HPRT1KDM4EMAPTHSD17B10HPGD
SCHEMBL4567324 0.95 KDM4E (0.50) HPRT1KDM4EMAPTHSD17B10HPGD
SCHEMBL18086160 0.93 ALDH1A1 (0.52) KDM4EMAPTHSD17B10HPGDGLA
SCHEMBL12071354 0.93 KDM4E (0.51) HPRT1KDM4EMAPTHSD17B10HPGD
SCHEMBL24362876 0.91 KDM4E (0.44) HPRT1KDM4EMAPTHSD17B10HPGD
SCHEMBL17229109 0.89 KDM4E (0.49) KDM4EMAPTHSD17B10HPGDGLA
SCHEMBL24362945 0.89 KDM4E (0.43) HPRT1KDM4EMAPTHSD17B10HPGD
SCHEMBL23759462 0.89 KDM4E (0.45) HPRT1KDM4EMAPTHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120119196-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 US disclosed
US-20120119196-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 US disclosed