Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.74 |
| ▸ | BACE1 | P56817 | 1/20 | 0.74 |
| ▸ | PPARG | P37231 | 8/20 | 0.72 |
| ▸ | CNR1 | P21554 | 2/20 | 0.72 |
| ▸ | CNR2 | P34972 | 2/20 | 0.72 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.72 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.72 |
| ▸ | INHA | P05111 | 1/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.72 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.72 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.72 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 6/20 | 0.64 |
| ▸ | APP | P05067 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218590 | 0.90 | PTPN1 (0.70) | PTPN1BACE1PPARGCNR1CNR2 | |
| SCHEMBL23523066 | 0.88 | PPARG (0.66) | PTPN1BACE1PPARGCNR1CNR2 | |
| SCHEMBL6274094 | 0.88 | MAOB (0.80) | PTPN1BACE1PPARGCNR1CNR2 | |
| SCHEMBL23888288 | 0.88 | MAOB (0.80) | PTPN1BACE1PPARGCNR1CNR2 | |
| SCHEMBL17329461 | 0.88 | PPARG (0.82) | PTPN1BACE1PPARGCNR1CNR2 | |
| SCHEMBL6856702 | 0.88 | PPARG (0.82) | PTPN1BACE1PPARGCNR1CNR2 | |
| SCHEMBL23522862 | 0.87 | PTPN1 (0.97) | PTPN1BACE1PPARGCNR1CNR2 | |
| SCHEMBL19846964 | 0.87 | PTPN1 (0.97) | PTPN1BACE1PPARGCNR1CNR2 | |
| SCHEMBL24997815 | 0.86 | PPARG (0.71) | PTPN1BACE1PPARGCNR1CNR2 | |
| Grifolin SCHEMBL21065400 | 0.85 | PTPN1 (1.00) | PTPN1BACE1PPARGCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173867-B2 | Treatment of immune dysregulation using cannabinoid derivatives | IMMUGEN PHARMACEUTICALS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-9173867-B2 | Treatment of immune dysregulation using cannabinoid derivatives | IMMUGEN PHARMACEUTICALS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20140066497-A1 | TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES | IMMUGEN PHARMACEUTICALS, INC. | 2014-03-06 | — | — | US | disclosed |
| US-20140066497-A1 | TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES | IMMUGEN PHARMACEUTICALS, INC. | 2014-03-06 | — | — | US | disclosed |
| US-8586767-B2 | Method for treatment of HIV and diseases of immune dysregulation | TRAVIS CRAIG RICK (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120289589-A1 | Treatment Of Immune Dysregulation Using Cannabinoid Derivatives | TRAVIS CRAIG RICK (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120289589-A1 | Treatment Of Immune Dysregulation Using Cannabinoid Derivatives | TRAVIS CRAIG RICK (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120122917-A1 | Method For Treatment Of HIV And Diseases Of Immune Dysregulation | TRAVIS CRAIG RICK (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120122917-A1 | Method For Treatment Of HIV And Diseases Of Immune Dysregulation | TRAVIS CRAIG RICK (US) | 2012-05-17 | — | — | US | disclosed |
| US-20080108647-A1 | Treatment of HIV and diseases of immune dysregulation | TRAVIS CRAIG R | 2008-05-08 | — | — | US | disclosed |
| US-20080108647-A1 | Treatment of HIV and diseases of immune dysregulation | TRAVIS CRAIG R | 2008-05-08 | — | — | US | disclosed |
| US-20070179135-A1 | Cannabinoid derivatives | TRAVIS CRAIG R | 2007-08-02 | — | — | US | disclosed |
| US-20070179135-A1 | Cannabinoid derivatives | TRAVIS CRAIG R | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066497-A1 | TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES | CNR2, CNR1, GPR18 | PTPN1 649/4885BACE1 1796/4885PPARG 356/4885 |
| US-20120289589-A1 | Treatment Of Immune Dysregulation Using Cannabinoid Derivatives | CNR2, CNR1, GPR18 | PTPN1 649/4885BACE1 1796/4885PPARG 356/4885 |
| US-20120122917-A1 | Method For Treatment Of HIV And Diseases Of Immune Dysregulation | CNR2, CNR1, ICOS | PTPN1 1786/4885BACE1 1156/4885PPARG 1180/4885 |
| US-20070179135-A1 | Cannabinoid derivatives | CNR2, CNR1, GPR18 | PTPN1 3487/4885BACE1 1121/4885PPARG 110/4885 |
| US-20080108647-A1 | Treatment of HIV and diseases of immune dysregulation | CNR1, CNR2, ICOS | PTPN1 1134/4885BACE1 1118/4885PPARG 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.