SCHEMBL4567367

SCHEMBL4567367

CN=Nc1ccc(N)c2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
NPC1 O15118 2/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
MAPT P10636 1/20 0.66
MAPK1 P28482 1/20 0.66
INSR P06213 1/20 0.49
GLO1 Q04760 2/20 0.48
SENP3 Q9H4L4 3/20 0.46
SENP2 Q9HC62 3/20 0.46
SENP1 Q9P0U3 3/20 0.46
SUMO2 P61956 2/20 0.46
SUMO1 P63165 2/20 0.46
SENP7 Q9BQF6 2/20 0.46
IDO1 P14902 2/20 0.45
CHEK1 O14757 1/20 0.45
NEK2 P51955 1/20 0.45
LIMK1 P53667 1/20 0.45
DYRK1A Q13627 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8653147 0.89 TDP1 (0.80) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL14020317 0.89 MEN1 (0.48) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL3694949 0.81 MEN1 (0.89) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL3694952 0.81 MEN1 (0.89) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL3694948 0.81 MEN1 (0.89) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL31073963 0.79 MEN1 (1.00) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL243332 0.79 MEN1 (1.00) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL15274139 0.79 MEN1 (1.00) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL29362584 0.79 MEN1 (1.00) TDP1MEN1KMT2ANPC1L3MBTL1
SCHEMBL243333 0.79 MEN1 (1.00) TDP1MEN1KMT2ANPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140046042-A1 LIQUID-CRYSTALLINE COATING FLUID AND POLARIZING FILM NITTO DENKO CORPORATION (JP) 2014-02-13 US disclosed
US-8556406-B2 Coloring matter consisting of trisazo compound, ink compositions, recording method, and colored body NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-10-15 US disclosed
US-20120216714-A1 LIQUID-CRYSTALLINE COATING FLUID AND POLARIZING FILM NITTO DENKO CORPORATION (JP) 2012-08-30 US disclosed
US-20120216714-A1 LIQUID-CRYSTALLINE COATING FLUID AND POLARIZING FILM NITTO DENKO CORPORATION (JP) 2012-08-30 US disclosed
US-20120120148-A1 COLORING MATTER CONSISTING OF TRISAZO COMPOUND, INK COMPOSITIONS, RECORDING METHOD, AND COLORED BODY NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-05-17 US disclosed
US-7553340-B2 Reactive dyes, a process for their preparation and their use HUNTSMAN INTERNATIONAL, LLC (US) 2009-06-30 US disclosed
US-20070294842-A1 Reactive Dyes, a Process for Their Preparation and Their Use HUNTSMAN INTERNATIONAL LLC 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070294842-A1 Reactive Dyes, a Process for Their Preparation and Their Use CBR3, ARSA, CBR1 TDP1 2975/4885MEN1 4643/4885KMT2A 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.