SCHEMBL4567509

SCHEMBL4567509

Cc1cc(O)n2c(nc3ccccc32)c1C#N

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.73
ALDH1A1 P00352 10/20 0.73
GAA P10253 7/20 0.73
POLB P06746 5/20 0.73
MAPT P10636 4/20 0.73
GLA P06280 3/20 0.73
SMN1; SMN2 Q16637 2/20 0.73
XBP1 P17861 1/20 0.73
NPSR1 Q6W5P4 1/20 0.73
KLK7 P49862 2/20 0.70
KMT2A Q03164 4/20 0.65
HPGD P15428 6/20 0.62
CASP1 P29466 3/20 0.62
CASP7 P55210 3/20 0.62
MAPK1 P28482 2/20 0.62
MEN1 O00255 2/20 0.62
AURKA O14965 1/20 0.62
PIM1 P11309 1/20 0.62
MAPKAPK2 P49137 1/20 0.62
PLK1 P53350 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13019377 0.87 KDM4E (0.75) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL2162680 0.84 KDM4E (1.00) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL12468226 0.84 KDM4E (0.76) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL2163413 0.84 KDM4E (0.71) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL12324282 0.83 MAPT (0.67) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL2163751 0.82 KDM4E (0.76) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL2163357 0.82 KLK7 (1.00) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL14478944 0.81 MAPT (1.00) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL10105959 0.80 MAPT (0.60) KDM4EALDH1A1GAAPOLBMAPT
SCHEMBL14478818 0.80 HSD17B10 (0.77) KDM4EALDH1A1GAAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10240053-B2 Aqueous ink, ink cartridge, and ink jet recording method CANON KABUSHIKI KAISHA (JP) 2019-03-26 US disclosed
EP-2674462-B1 Ink, ink cartridge and ink jet recording method CANON KK (JP) 2016-12-14 EP disclosed
US-8932393-B2 Azo compound, ink composition, recording method and colored material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-01-13 US disclosed
US-8932393-B2 Azo compound, ink composition, recording method and colored material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-01-13 US disclosed
US-8864891-B2 Ink composition, inkjet recording method and colored body NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-10-21 US disclosed
US-8864891-B2 Ink composition, inkjet recording method and colored body NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-10-21 US disclosed
US-8814341-B2 Ink, ink cartridge and ink jet recording method CANON KABUSHIKI KAISHA (JP) 2014-08-26 US disclosed
US-8814341-B2 Ink, ink cartridge and ink jet recording method CANON KABUSHIKI KAISHA (JP) 2014-08-26 US disclosed
US-8556406-B2 Coloring matter consisting of trisazo compound, ink compositions, recording method, and colored body NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-10-15 US disclosed
US-8556406-B2 Coloring matter consisting of trisazo compound, ink compositions, recording method, and colored body NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-10-15 US disclosed
US-7550037-B2 Ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-06-23 US disclosed
US-7550037-B2 Ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-06-23 US disclosed
US-20090062545-A1 Trisazo Compound, Ink Composition, Recording Method, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-03-05 US disclosed
US-20090062545-A1 Trisazo Compound, Ink Composition, Recording Method, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-03-05 US disclosed
US-20090011130-A1 INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-01-08 US disclosed
US-20090011130-A1 INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-01-08 US disclosed
EP-2011841-A2 Ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus Canon Kabushiki Kaisha (JP) 2009-01-07 EP disclosed
EP-1975205-A1 TRISAZO COMPOUND, INK COMPOSITION, RECORDING METHOD AND COLORED MATTER Nipponkayaku Kabushikikaisha (JP) 2008-10-01 EP disclosed
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062545-A1 Trisazo Compound, Ink Composition, Recording Method, and Colored Article JAK1, TMT1A, CDK1 KDM4E 1223/4885ALDH1A1 2569/4885GAA 4787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.