Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.75 |
| ▸ | GAA | P10253 | 8/20 | 0.75 |
| ▸ | POLB | P06746 | 5/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | GLA | P06280 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | XBP1 | P17861 | 1/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | KLK7 | P49862 | 2/20 | 0.71 |
| ▸ | CASP1 | P29466 | 4/20 | 0.67 |
| ▸ | CASP7 | P55210 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 7/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4567509 | 0.87 | KDM4E (0.73) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL2163413 | 0.86 | KDM4E (0.71) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL2162680 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL12468226 | 0.86 | KDM4E (0.76) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL2163751 | 0.83 | KDM4E (0.76) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL2163357 | 0.83 | KLK7 (1.00) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL29683890 | 0.80 | MAPT (0.83) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL29721630 | 0.80 | KLK7 (0.76) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL12324282 | 0.79 | MAPT (0.67) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL14478949 | 0.79 | KDM4E (0.75) | KDM4EALDH1A1GAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | KDM4E 3763/4885ALDH1A1 391/4885GAA 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.