⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19486970 | 0.72 | — | — | |
| SCHEMBL18015092 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL12595236 | 0.69 | — | — | |
| SCHEMBL7945407 | 0.69 | — | — | |
| SCHEMBL8054959 | 0.69 | — | — | |
| SCHEMBL24832459 | 0.69 | — | — | |
| SCHEMBL18538234 | 0.69 | — | — | |
| SCHEMBL21003971 | 0.67 | — | — | |
| SCHEMBL20841646 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3993749 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247577-B2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2022-04-27 | — | — | EP | claimed |
| EP-2247577-B1 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-12-23 | — | — | EP | claimed |
| CN-104277001-A | Method for the regioselective synthesis of 1-alkyl-3-haloalkyl-pyroazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AKTENGESELLSCHAFT | 2015-01-14 | — | — | CN | claimed |
| US-8629288-B2 | Method for the regioselective synthesis of 1-alky1-3-haloalkyl-pyrazole-4-carboxylic acid derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | claimed |
| CN-102026981-A | Regioselective preparation of 1-alkyl-3-haloalkylpyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AKTENGESELLS | 2011-04-20 | — | — | CN | claimed |
| US-20110009642-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-haloalkyl-pyrazole-4-carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | US | claimed |
| EP-2133341-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | claimed |
| US-20040242833-A1 | Production of masked isocyanates particularly masked polyisocyanates | RHODIA CHIMIE (FR) | 2004-12-02 | — | — | US | claimed |
| JP-1168673-A | — | — | None | — | — | JP | disclosed |
| US-20230340055-A1 | GLYCOSYLATED IL-2 PROTEINS AND USES THEREOF | Ascendis Pharma Oncology Division A/S (DK) | 2023-10-26 | — | — | US | disclosed |
| US-20230312499-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2023-10-05 | — | — | US | disclosed |
| US-20230302091-A1 | Combination Therapy with Controlled-Release CNP Agonists | ASCENDIS PHARMA GROWTH DISORDERS AS (DK) | 2023-09-28 | — | — | US | disclosed |
| US-20230248836-A1 | Dosage Regimen for a Controlled-Release PTH Compound | ASCENDIS PHARMA BONE DISEASES A/S (DK) | 2023-08-10 | — | — | US | disclosed |
| US-20230218722-A1 | PTH Compounds with Low Peak-To-Trough Ratios | ASCENDIS PHARMA BONE DISEASES AS (DK) | 2023-07-13 | — | — | US | disclosed |
| US-5043372-A | Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0434079-A1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| JP-H01168673-A | PRODUCTION OF 1,3-DIALKYLPYRAZOLE-4-ALDEHYDES | MITSUI TOATSU CHEM INC | 1989-07-04 | — | — | JP | disclosed |
| US-4101675-A | ANTIHYPERTENSIVES | AKZONA INCORPORATED (US) | 1978-07-18 | — | — | US | disclosed |
| US-3972932-A | Novel 2,6-disubstituted phenyl-aminoguanidine compounds | AKZONA INCORPORATED (US) | 1976-08-03 | — | — | US | disclosed |
| US-3943132-A | Process for the preparation of hydrazones | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-03-09 | — | — | US | disclosed |