Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456921 | 1.00 | REN (0.45) | REN | |
| SCHEMBL456922 | 1.00 | REN (0.45) | REN | |
| SCHEMBL1454882 | 0.84 | REN (0.55) | REN | |
| SCHEMBL862294 | 0.84 | REN (0.55) | REN | |
| SCHEMBL1454881 | 0.84 | REN (0.55) | REN | |
| SCHEMBL6855685 | 0.81 | REN (0.33) | REN | |
| SCHEMBL856948 | 0.78 | REN (0.45) | REN | |
| SCHEMBL8268412 | 0.76 | REN (0.43) | REN | |
| SCHEMBL8268391 | 0.75 | REN (0.43) | REN | |
| SCHEMBL2738428 | 0.74 | REN (0.48) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012034065-A1 | ALISKIREN INTERMEDIATES AND A PROCESS FOR ANALYZING THE PURITY OF ALISKIREN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2012-03-15 | — | — | WO | disclosed |