SCHEMBL4569588

SCHEMBL4569588

Cc1ccc(-c2ccc(S(=O)(=O)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.84
ALDH1A1 P00352 3/20 0.59
MEN1 O00255 1/20 0.59
MAPT P10636 1/20 0.59
KMT2A Q03164 1/20 0.59
PKM P14618 2/20 0.59
RAPGEF4 Q8WZA2 1/20 0.56
HTT P42858 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CA2 P00918 4/20 0.54
CA1 P00915 2/20 0.54
CA12 O43570 1/20 0.54
CA3 P07451 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
TLR9 Q9NR96 1/20 0.52
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15458757 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL19651363 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL4401275 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL19651364 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL9693261 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL170033 0.92 GAA (1.00) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL10067072 0.92 GAA (1.00) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL4400955 0.92 GAA (1.00) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL12336795 0.91 GAA (0.70) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL28479802 0.91 GAA (0.70) GAAALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134844-A1 Block Copolymer, Ion-Exchange Membrane And Method Of Preparing Block Copolymer KOREA INSTITUTE OF ENERGY RESEARCH (KR) 2018-05-17 US disclosed
US-20170342324-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-11-30 US disclosed
US-9178238-B2 Rubber crack mitigants in polyelectrolyte membranes GM GLOBAL TECHNOLOGY OPERATIONS, LLC (US) 2015-11-03 US disclosed
US-9178238-B2 Rubber crack mitigants in polyelectrolyte membranes GM GLOBAL TECHNOLOGY OPERATIONS, LLC (US) 2015-11-03 US disclosed
US-9172099-B2 Nano-fibers for electrical power generation GM Global Technology Operations LLC (US) 2015-10-27 US disclosed
US-9172099-B2 Nano-fibers for electrical power generation GM Global Technology Operations LLC (US) 2015-10-27 US disclosed
US-20150171454-A1 MEMBRANE WITH LAMINATED STRUCTURE AND ORIENTATION CONTROLLED NANOFIBER REINFORCEMENT ADDITIVES FOR FUEL CELLS GM GLOBAL TECH OPERATIONS INC (US) 2015-06-18 US disclosed
US-20150171454-A1 MEMBRANE WITH LAMINATED STRUCTURE AND ORIENTATION CONTROLLED NANOFIBER REINFORCEMENT ADDITIVES FOR FUEL CELLS GM GLOBAL TECH OPERATIONS INC (US) 2015-06-18 US disclosed
US-9040209-B2 Multi-layer polyelectrolyte membranes GM Global Technology Operations LLC (US) 2015-05-26 US disclosed
US-9040209-B2 Multi-layer polyelectrolyte membranes GM Global Technology Operations LLC (US) 2015-05-26 US disclosed
US-20100047657-A1 GRADIENT REINFORCED PROTON EXCHANGE MEMBRANE GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2010-02-25 US disclosed
US-20100041837-A1 POLYARYLETHERS, BLENDS AND METHODS FOR MAKING GENERAL ELECTRIC COMPANY 2010-02-18 US disclosed
US-20090280383-A1 BLENDED PEM'S WITH ELASTOMERS FOR IMPROVED MECHANICAL DURABILITY GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090281270-A1 SULFONATED-POLYPERFLUORO-CYCLOBUTANE-POLYPHENLENE POLYMERS FOR PEM FUEL CELL APPLICATIONS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090281262-A1 PROTON CONDUCTIVE POLYMER ELECTROLYTES AND FUEL CELLS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090281262-A1 PROTON CONDUCTIVE POLYMER ELECTROLYTES AND FUEL CELLS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090280382-A1 COMPOSITE MEMBRANE GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090278083-A1 POLYELECTROLYTE MEMBRANES COMPRISED OF BLENDS OF PFSA AND SULFONATED PFCB POLYMERS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20080193702-A1 Poly(Aryletherdisulfone) Composition and Shaped Article Made Thereof SOLVAY ADVANDED POLYMERS, L.L.C. (US) 2008-08-14 US disclosed
US-20080193702-A1 Poly(Aryletherdisulfone) Composition and Shaped Article Made Thereof SOLVAY ADVANDED POLYMERS, L.L.C. (US) 2008-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170342324-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MTX1, S100A11, MCRS1 GAA 4409/4885ALDH1A1 3730/4885MEN1 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.