SCHEMBL9693261

SCHEMBL9693261

Cc1ccc(-c2ccc(S(=O)(=O)c3ccc(-c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.84
ALDH1A1 P00352 3/20 0.59
MEN1 O00255 1/20 0.59
MAPT P10636 1/20 0.59
KMT2A Q03164 1/20 0.59
PKM P14618 2/20 0.59
RAPGEF4 Q8WZA2 1/20 0.56
HTT P42858 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CA2 P00918 4/20 0.54
CA1 P00915 2/20 0.54
CA12 O43570 1/20 0.54
CA3 P07451 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
TLR9 Q9NR96 1/20 0.52
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15458757 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL19651363 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL4569588 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL4401275 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL19651364 1.00 GAA (0.84) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL170033 0.92 GAA (1.00) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL10067072 0.92 GAA (1.00) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL4400955 0.92 GAA (1.00) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL12336795 0.91 GAA (0.70) GAAALDH1A1MEN1MAPTKMT2A
SCHEMBL28479802 0.91 GAA (0.70) GAAALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170342324-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-11-30 US disclosed
US-5084530-A Polyether ketone resins for molding materials and extrusion composites AMOCO CORPORATION (US) 1992-01-28 US disclosed
US-5037936-A Bis(acid chloride) terminated polyaryl ether ketone oligomer AMOCO CORPORATION (US) 1991-08-06 US disclosed
US-4975470-A TOUGHNESS, HEAT RESISTANCE, STRESS RESISTANCE, NONCRACKING AMOCO CORPORATION (US) 1990-12-04 US disclosed
US-4968758-A MOLODING MATERIALS WITH EXCELLENT HEAT, SOLVENT, AND STRESS-CRACK RESISTANCE AMOCO CORPORATION (US) 1990-11-06 US disclosed
EP-0195448-B1 PROCESS FOR PREPARING POLY (ARYL ETHER KETONE)S AMOCO CORPORATION (US) 1990-06-20 EP disclosed
EP-0244167-B1 IMPROVED PROCESS FOR PREPARING POLY (ARYL ETHERS) AND POLY (ARYL ETHER KETONES) AMOCO CORPORATION (US) 1990-04-04 EP disclosed
EP-0275295-A4 BLENDS CONTAINING LIQUID CRYSTALLINE POLYESTERS. AMOCO CORP (US) 1990-02-21 EP disclosed
US-4870155-A RANDOM POLYMER OF DIIMIDE-CONTAINING MONOMER, DIHYDRIC PHENOLS AND ACTIVATED DIHALO- OR DINITROBENZOIDS; MELT FABRICABILITY AMOCO CORPORATION (US) 1989-09-26 US disclosed
US-4861915-A Poly (aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1989-08-29 US disclosed
US-4774314-A POLYETHER KETONE POLYMERS AMOCO CORPORATION (US) 1988-09-27 US disclosed
EP-0275295-A1 BLENDS CONTAINING LIQUID CRYSTALLINE POLYESTERS AMOCO CORPORATION (US) 1988-07-27 EP disclosed
US-4748227-A Process for preparing poly(aryl ether)ketones using a sodium carbonate/organic acid salt catalyst AMOCO CORPORATION (US) 1988-05-31 US disclosed
WO-1988000605-A1 BLENDS CONTAINING LIQUID CRYSTALLINE POLYESTERS AMOCO CORPORATION (US) 1988-01-28 WO disclosed
EP-0244167-A1 Improved process for preparing poly (aryl ethers) and poly (aryl ether ketones) AMOCO CORPORATION (US) 1987-11-04 EP disclosed
EP-0213637-A2 Novel polyetherimides AMOCO CORPORATION (US) 1987-03-11 EP disclosed
EP-0211693-A1 Preparation of poly(aryl ether ketones) AMOCO CORPORATION (US) 1987-02-25 EP disclosed
US-4642327-A HIGH TEMPERATURE MOLDING MATERIALS AMOCO CORPORATION (US) 1987-02-10 US disclosed
US-4638044-A Process for preparing poly(aryl ether ketone)s AMOCO CORPORATION (US) 1987-01-20 US disclosed
EP-0195448-A2 Process for preparing poly (aryl ether ketone)s AMOCO CORPORATION (US) 1986-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170342324-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MTX1, S100A11, MCRS1 GAA 4409/4885ALDH1A1 3730/4885MEN1 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.