Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 9/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565345 | 0.84 | KMT2A (0.45) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL4565515 | 0.83 | KMT2A (0.44) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL4540327 | 0.83 | CHRM1 (0.47) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL13707674 | 0.82 | KMT2A (0.46) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL4542156 | 0.82 | KMT2A (0.48) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL4569742 | 0.81 | KMT2A (0.46) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL4565788 | 0.81 | KMT2A (0.46) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL4564992 | 0.80 | KMT2A (0.43) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL4543903 | 0.80 | KMT2A (0.44) | KMT2AMEN1PPARGNR2E3NCOR2 | |
| SCHEMBL4569705 | 0.78 | KDM4E (0.54) | KMT2AMEN1PPARGNR2E3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |