Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13707722 | 0.95 | KDM4E (0.48) | KDM4EPKMTP53LMNAMEN1 | |
| SCHEMBL4569596 | 0.90 | MEN1 (0.55) | KDM4EPKMTP53LMNAMEN1 | |
| SCHEMBL4540327 | 0.81 | CHRM1 (0.47) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4569742 | 0.79 | KMT2A (0.46) | KDM4EMEN1KMT2AMAPTPPARG | |
| SCHEMBL4565788 | 0.79 | KMT2A (0.46) | MEN1KMT2AMAPTPPARGNR2E3 | |
| SCHEMBL4542294 | 0.79 | HTR4 (0.49) | TP53LMNAMEN1KMT2AMAPT | |
| SCHEMBL4569741 | 0.78 | KMT2A (0.42) | MEN1KMT2AMAPTPPARGNR2E3 | |
| SCHEMBL4543903 | 0.78 | KMT2A (0.44) | MEN1KMT2AMAPTPPARGNR2E3 | |
| SCHEMBL4565632 | 0.78 | MEN1 (0.60) | KDM4EPKMMEN1KMT2AMAPT | |
| SCHEMBL13707643 | 0.77 | MAPT (0.54) | PKMLMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |