SCHEMBL456987

SCHEMBL456987

CCC=Cc1ccccn1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
ATM Q13315 1/20 0.62
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
GRM4 Q14833 1/20 0.44
NR4A1 P22736 1/20 0.44
MAOA P21397 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TOP2A P11388 1/20 0.41
MAPT P10636 2/20 0.40
ALDH1A1 P00352 1/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.40
NFE2L2 Q16236 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL256048 1.00 NPC1 (0.62) NPC1RAB9AMEN1KMT2AATM
SCHEMBL2660767 0.83 MEN1 (0.58) NPC1RAB9AMEN1KMT2AATM
SCHEMBL2660769 0.83 MEN1 (0.58) NPC1RAB9AMEN1KMT2AATM
SCHEMBL30379649 0.83 MEN1 (0.58) NPC1RAB9AMEN1KMT2AATM
SCHEMBL270008 0.82
SCHEMBL2821529 0.81 NPC1 (0.46) NPC1RAB9AMEN1KMT2AATM
SCHEMBL6863156 0.80 MEN1 (0.54) NPC1RAB9AMEN1KMT2AATM
SCHEMBL6863164 0.80 MEN1 (0.54) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13699261 0.79 NPC1 (0.52) NPC1RAB9AMEN1KMT2AATM
SCHEMBL9466506 0.79 MEN1 (0.52) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060160954-A1 Preparation of graft copolymers by sequential polymerization using peroxide-containing polyolefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2006-07-20 US claimed
US-20060128824-A1 Irradiation process for making graft copolymers by sequential polymerization BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2006-06-15 US claimed
US-20060051648-A1 Solid polymer electrolyte membrane, method for producing the same, and fuel cell including the solid poymer electrolyte membrane SAMSUNG SDI CO. LTD. (KR) 2006-03-09 US claimed
WO-2005063376-A1 PROCESS FOR MAKING PEROXIDE-CONTAINING OLEFIN POLYMERS Basell Poliolefine Italia, s.r.l. (US) 2005-07-14 WO claimed
EP-0787750-B1 Poly(alkylethylene) structural isomers BOREALIS GMBH (AT) 2003-05-14 EP claimed
EP-0806439-B1 Process for making propylene graft copolymers using a redox initiator system BASELL NORTH AMERICA INC (US) 2002-09-11 EP claimed
US-5817707-A RADIATION; CONTROLLED OXIDATION; HEATING; DISPENSING IN WATER; ADDING VINYL MONOMER MONTELL NORTH AMERICA INC. (US) 1998-10-06 US claimed
EP-0806439-A2 Process for making propylene graft copolymers using a redox initiator system MONTELL NORTH AMERICA INC. (US) 1997-11-12 EP claimed
US-20250332546-A1 ION EXCHANGE MEMBRANE, METHOD FOR MANUFACTURING ION EXCHANGE MEMBRANE, AND ION EXCHANGE MEMBRANE CELL UNIV YAMAGUCHI (JP) 2025-10-30 US disclosed
EP-4331710-A1 ION EXCHANGE MEMBRANE, METHOD FOR MANUFACTURING ION EXCHANGE MEMBRANE, AND ION EXCHANGE MEMBRANE CELL Yamaguchi University (JP) 2024-03-06 EP disclosed
CN-113856752-B Pyridine polymer ionic liquid solid acid catalyst and preparation method and application thereof 常州大学 2024-01-23 CN disclosed
CN-113540562-B Electrolyte for lithium battery, and preparation method and application of electrolyte 中国石油化工股份有限公司 2024-01-09 CN disclosed
CN-116715622-A Synthesis method of 2- (2-arylbutyl) pyridine compound 河南大学 2023-09-08 CN disclosed
US-20230119424-A1 ANION EXCHANGE MEMBRANE AND METHOD FOR PRODUCING SAME ASTOM CORPORATION (JP) 2023-04-20 US disclosed
EP-0437808-A2 Graft copolymers of polyolefins and a method of producing same Himont Incorporated (US) 1991-07-24 EP disclosed
EP-0375290-A2 Electrode apparatus for dialysis TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-06-27 EP disclosed
EP-0164270-B1 PHOTO-POLYMERIZABLE COMPOSITON AND PRINTING PLATE PREPARED THEREFROM NAPP SYSTEMS INC. (US) 1990-05-02 EP disclosed
EP-0164270-A2 Photo-polymerizable compositon and printing plate prepared therefrom NAPP SYSTEMS INC. (US) 1985-12-11 EP disclosed
US-4179212-A Demand publishing royalty accounting system XEROX CORPORATION (US) 1979-12-18 US disclosed
US-3940377-A Method of activating polymers POLYMER RESEARCH CORPORATION OF AMERICA (US) 1976-02-24 US disclosed