SCHEMBL2821529

SCHEMBL2821529

C=Cc1ccccn1.CCC=Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ATM Q13315 1/20 0.46
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
MAPT P10636 1/20 0.39
GRM4 Q14833 1/20 0.37
HTR2A P28223 3/20 0.37
MAOA P21397 1/20 0.37
RELA Q04206 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8824964 0.82 NPC1 (0.50) NPC1RAB9AL3MBTL1TDP1MEN1
SCHEMBL456987 0.81 NPC1 (0.62) NPC1RAB9ATDP1MEN1KMT2A
SCHEMBL256048 0.81 NPC1 (0.62) NPC1RAB9ATDP1MEN1KMT2A
Styrene SCHEMBL11312642 0.79 ALDH1A1 (0.58) MEN1KMT2AHTR2ARELA
Styrene SCHEMBL5101848 0.79 ALDH1A1 (0.58) MEN1KMT2AHTR2ARELA
Styrene SCHEMBL607743 0.79 ALDH1A1 (0.58) NPC1RAB9AL3MBTL1TDP1MEN1
Benzene SCHEMBL27612258 0.79 MEN1 (0.64) NPC1RAB9ATDP1MEN1KMT2A
SCHEMBL27789592 0.79 NPC1 (0.50) NPC1RAB9AL3MBTL1TDP1MEN1
SCHEMBL2229188 0.79 NPC1 (0.50) NPC1RAB9AL3MBTL1TDP1MEN1
Alcohol SCHEMBL28036478 0.78 NPC1 (0.52) NPC1RAB9ATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108289801-B Oral care gel 高露洁-棕榄公司 2021-01-26 CN disclosed
US-20200360242-A1 Oral Care Gel COLGATE-PALMOLIVE COMPANY (US) 2020-11-19 US disclosed
EP-3377025-A1 ORAL CARE GEL Colgate-Palmolive Company (US) 2018-09-26 EP disclosed
WO-2017095405-A1 ORAL CARE GEL COLGATE-PALMOLIVE COMPANY (US) 2017-06-08 WO disclosed
EP-1835968-B2 TOOTH WHITENING COMPOSITION CONTAINING CROSS-LINKED POLYMER-PEROXIDES COLGATE PALMOLIVE CO (US) 2015-04-01 EP disclosed
US-8568695-B2 Oral care composition with silicone composite COLGATE-PALMOLIVE COMPANY (US) 2013-10-29 US disclosed
EP-2012745-B1 ORAL CARE COMPOSITION WITH SILICONE COMPOSITE COLGATE PALMOLIVE CO (US) 2010-10-27 EP disclosed
EP-1835968-B1 TOOTH WHITENING COMPOSITION CONTAINING CROSS-LINKED POLYMER-PEROXIDES COLGATE PALMOLIVE CO (US) 2010-08-18 EP disclosed
EP-2012745-A1 ORAL CARE COMPOSITION WITH SILICONE COMPOSITE Colgate-Palmolive Company (US) 2009-01-14 EP disclosed
WO-2007130816-A1 ORAL CARE COMPOSITION WITH SILICONE COMPOSITE COLGATE-PALMOLIVE COMPANY (US) 2007-11-15 WO disclosed
US-5955552-A SHEARING A BIPHASIC LIQUID SYSTEM OF AN AQUEOUS SOLUTION AND A POLYUNSATURATED MONOMER DISSOLVED IN A WATER-IMMISCIBLE ORGANIC SOLVENT TO SUSPEND THE ORGANIC PHASE AS MICRODROPLETS; POLYMERIZATION AMCOL INTERNATIONAL CORPORATION (US) 1999-09-21 US disclosed
US-5837790-A ALLYL METHACRYLATE COPOLYMER WITH ETHYLENE GLYCOL, DIMETHACRYLATE AS OIL ADSORBENT AMCOL INTERNATIONAL CORPORATION (US) 1998-11-17 US disclosed
US-5834577-A COMPRISING COPOLYMER OF ALLYL METHACRYLATE AND ETHYLENE GLYCOL DIMETHACRYLATE AMCOL INTERNATIONAL CORPORATION (US) 1998-11-10 US disclosed
US-5830960-A POLYMERIZING POLYUNSATURATED MONOMER IN SILICONE SOLVENT AMCOL INTERNATIONAL CORPORATION (US) 1998-11-03 US disclosed
US-5830967-A BUTYL METHACRYLATE-ALLYL METHACRYLATE-(OLIGO)ETHYLENE GLYCOL DIMETHACRYLATE TERPOLYMER AMCOL INTERNATIONAL CORPORATION (US) 1998-11-03 US disclosed
EP-0863159-A2 Precipitation polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and liquids and the product thereof AMCOL INTERNATIONAL CORPORATION (US) 1998-09-09 EP disclosed
EP-0863160-A2 Process for producing an oil sorbent copolymer and the product thereof AMCOL INTERNATIONAL CORPORATION (US) 1998-09-09 EP disclosed
US-5712358-A ALLYL METHACRYLATE AND AN ETHYLENE GLYCOL DIMETHACRYLATE, INTERFACIAL POLYMERIZATION, CROSSLINKING, POROSITY AMCOL INTERNATIONAL CORPORATION (US) 1998-01-27 US disclosed
US-5261169-A System and method for deodorant delivery in footwear ADVANCED POLYMER SYSTEMS, INC. (US) 1993-11-16 US disclosed
WO-1993006757-A1 SYSTEM AND METHOD FOR DEODORANT DELIVERY IN FOOTWEAR ADVANCED POLYMER SYSTEMS, INC. (US) 1993-04-15 WO disclosed