Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.48 |
| ▸ | PGR | P06401 | 5/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216794 | 0.82 | NR3C1 (0.52) | NR3C1PGRNR3C2L3MBTL1 | |
| SCHEMBL3223796 | 0.79 | NR3C1 (0.56) | NR3C1PGRNR3C2 | |
| SCHEMBL3223117 | 0.75 | NR3C1 (0.68) | NR3C1PGRNR3C2ITGB3ITGAV | |
| SCHEMBL3219746 | 0.72 | NR3C1 (0.50) | NR3C1PGRNR3C2L3MBTL1 | |
| SCHEMBL3226726 | 0.69 | NR3C1 (0.80) | NR3C1PGRNR3C2 | |
| SCHEMBL3213631 | 0.69 | NR3C1 (0.63) | NR3C1PGRNR3C2L3MBTL1CYP3A4 | |
| SCHEMBL14044212 | 0.69 | NR3C1 (0.44) | NR3C1PGRNR3C2 | |
| SCHEMBL3224585 | 0.69 | NR3C1 (0.48) | NR3C1PGRNR3C2ITGB3ITGAV | |
| SCHEMBL3226911 | 0.67 | NR3C1 (0.52) | NR3C1PGRNR3C2 | |
| SCHEMBL3220617 | 0.67 | NR3C1 (0.44) | NR3C1PGRNR3C2ITGAVCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136811-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008124745-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |