Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21052634 | 1.00 | HRH1 (0.61) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2903487 | 0.98 | HRH1 (0.58) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL154864 | 0.93 | HRH1 (0.55) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL29742236 | 0.85 | SMN1; SMN2 (0.54) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2508761 | 0.85 | HRH1 (0.55) | HRH1CYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL4418086 | 0.84 | HRH1 (0.80) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL659243 | 0.84 | HRH1 (0.80) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2843489 | 0.84 | HRH1 (0.80) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL31040594 | 0.84 | HRH1 (0.80) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL11734076 | 0.84 | HRH1 (0.80) | HRH1NAAACYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033800-A1 | COMPOSITION AND METHOD FOR INHIBITING PREMATURE POLYMERIZATION | GENERAL ELECTRIC COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |