SCHEMBL4570514

SCHEMBL4570514

Cc1ccccc1-c1cccc2ccc3c4ccc5ccccc5c4ccc3c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.52
HSD17B10 Q99714 8/20 0.52
HPGD P15428 6/20 0.52
CYP1A2 P05177 6/20 0.52
THRB P10828 1/20 0.52
CYP2A6 P11509 4/20 0.50
HPRT1 P00492 3/20 0.50
TSHR P16473 7/20 0.47
L3MBTL1 Q9Y468 4/20 0.47
MAPK1 P28482 4/20 0.47
CASP1 P29466 3/20 0.47
HIF1A Q16665 3/20 0.47
FYN P06241 2/20 0.47
ACHE P22303 2/20 0.47
AHR P35869 2/20 0.47
ERBB2 P04626 1/20 0.47
MAOA P21397 1/20 0.47
CYP3A4 P08684 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ATM Q13315 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28322645 0.89 HPRT1 (0.58) ALDH1A1HSD17B10HPGDCYP1A2THRB
Fluoranthene SCHEMBL9855068 0.86 ALDH1A1 (0.55) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL598916 0.85 ALDH1A1 (0.60) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL22978748 0.82 CYP1A2 (0.48) ALDH1A1HSD17B10HPGDCYP1A2THRB
Triphenylene SCHEMBL5783342 0.81 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL28581429 0.81 HPRT1 (0.64) ALDH1A1HSD17B10HPGDCYP1A2THRB
Chrysene SCHEMBL16034318 0.81 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL29907083 0.81 HPRT1 (0.64) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL12990204 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10HPGDCYP1A2CYP2A6
SCHEMBL31440283 0.80 ALDH1A1 (0.59) ALDH1A1HSD17B10HPGDCYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8723027-B2 Photovoltaic applications of non-conjugated conductive polymers THAKUR MRINAL (US) 2014-05-13 US disclosed
US-20130153862-A1 PHOTOVOLTAIC APPLICATIONS OF NON-CONJUGATED CONDUCTIVE POLYMERS THAKUR MRINAL (US) 2013-06-20 US disclosed
US-20090205698-A1 PHOTOVOLTAIC APPLICATIONS OF NON-CONJUGATED CONDUCTIVE POLYMERS THAKUR MRINAL 2009-08-20 US disclosed