Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10044383 | 0.85 | FGFR1 (0.72) | FGFR1 | |
| SCHEMBL138629 | 0.84 | FGFR1 (1.00) | FGFR1 | |
| SCHEMBL254710 | 0.74 | FGFR1 (0.81) | FGFR1 | |
| SCHEMBL14308878 | 0.73 | FGFR1 (0.71) | FGFR1 | |
| SCHEMBL23541604 | 0.71 | FGFR1 (0.58) | FGFR1 | |
| SCHEMBL26803955 | 0.71 | FGFR1 (0.65) | FGFR1 | |
| SCHEMBL1105227 | 0.71 | FGFR1 (0.70) | FGFR1 | |
| SCHEMBL24140186 | 0.70 | FGFR1 (0.68) | FGFR1 | |
| SCHEMBL24140174 | 0.70 | FGFR1 (0.68) | FGFR1 | |
| SCHEMBL24140143 | 0.70 | FGFR1 (0.68) | FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318700-B2 | Lung-targeted drugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120122818-A1 | LUNG-TARGETED DRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122818-A1 | LUNG-TARGETED DRUGS | DGKG, GK, PHOSPHO1 | FGFR1 822/4885PTPN1 433/4885CDC25B 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.