Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | PLK4 | O00444 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414774 | 0.91 | CAMKK2 (0.55) | CAMKK2RIPK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL298899 | 0.90 | CAMKK2 (0.56) | CAMKK2RIPK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3702186 | 0.88 | CAMKK2 (0.67) | CAMKK2RIPK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL298449 | 0.88 | CYP2C9 (0.53) | CAMKK2RIPK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL856349 | 0.86 | CYP2C9 (0.62) | CAMKK2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL4570626 | 0.85 | CAMKK2 (0.61) | CAMKK2RIPK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4570623 | 0.85 | AXL (0.57) | CAMKK2RIPK1CYP3A4PLK4CYP2D6 | |
| SCHEMBL415640 | 0.84 | CAMKK2 (0.56) | CAMKK2RIPK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL299098 | 0.83 | CYP3A4 (0.51) | CAMKK2RIPK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2883018 | 0.83 | CYP2C9 (0.59) | CAMKK2CYP3A4CYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122860-A1 | SOLID FORMS OF SULFONAMIDES AND AMINO ACIDS | PLEXXIKON, INC. | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122860-A1 | SOLID FORMS OF SULFONAMIDES AND AMINO ACIDS | BRAF, RAF1, ARAF | CAMKK2 497/4885RIPK1 637/4885CYP3A4 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.