Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.57 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29209094 | 0.85 | NQO1 (0.64) | NQO1HSD17B3KDM4EMAPTCYP3A4 | |
| SCHEMBL17861953 | 0.85 | NQO1 (0.51) | NQO1KDM4EMAPTCYP3A4MEN1 | |
| SCHEMBL3682321 | 0.83 | HSD17B3 (0.67) | ALDH1A2ALDH2ALDH1B1ALDH1A3HSD17B3 | |
| SCHEMBL29406593 | 0.83 | HSD17B3 (0.67) | ALDH1A2ALDH2ALDH1B1ALDH1A3HSD17B3 | |
| SCHEMBL11658187 | 0.82 | NQO1 (0.53) | NQO1KDM4EMAPTCYP3A4MEN1 | |
| SCHEMBL11330155 | 0.81 | KDM4E (0.56) | NQO1KDM4EMAPTCYP3A4MEN1 | |
| SCHEMBL19635944 | 0.81 | HSD17B3 (0.60) | NQO1HSD17B3KDM4EMAPTCYP3A4 | |
| SCHEMBL30876199 | 0.81 | HSD17B3 (0.60) | NQO1HSD17B3KDM4EMAPTCYP3A4 | |
| SCHEMBL27950169 | 0.81 | NQO1 (0.48) | NQO1KDM4EMAPTCYP3A4MEN1 | |
| SCHEMBL10795110 | 0.80 | HSD17B3 (0.73) | ALDH1A2ALDH2ALDH1B1ALDH1A3HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168627-B2 | Helix 12 directed non-steroidal antiandrogens | ENDORECHERCHE, INC. (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20100227855-A1 | HELIX 12 DIRECTED NON-STEROIDAL ANTIANDROGENS | ENDORECHERCHE, INC. (CA) | 2010-09-09 | — | — | US | disclosed |
| US-7709516-B2 | Helix 12 directed non-steroidal antiandrogens | ENDORECHERCHE, INC. (CA) | 2010-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227855-A1 | HELIX 12 DIRECTED NON-STEROIDAL ANTIANDROGENS | AR, SHBG, CYP17A1 | NQO1 947/4885ALDH1A2 1701/4885ALDH2 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.