Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | SELL | P14151 | 1/20 | 0.51 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | SELE | P16581 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238755 | 0.85 | MEN1 (0.59) | NR1H4EPHX2KMT2AHDAC1HDAC6 | |
| SCHEMBL1058497 | 0.85 | ALDH1A1 (0.67) | KMT2ALMNARAB9A | |
| SCHEMBL26604271 | 0.80 | RARB (0.64) | KMT2A | |
| SCHEMBL10099575 | 0.80 | NR1H4 (0.84) | NR1H4EPHX2KMT2AHDAC1HDAC6 | |
| SCHEMBL16088685 | 0.79 | APEX1 (0.74) | KMT2APPARGLMNA | |
| SCHEMBL6245871 | 0.79 | NR1H4 (0.71) | NR1H4EPHX2KMT2AHDAC1HDAC6 | |
| SCHEMBL4747957 | 0.79 | NR1H4 (0.81) | NR1H4EPHX2KMT2AHDAC1HDAC6 | |
| SCHEMBL22987225 | 0.78 | PPARG (0.81) | NR1H4EPHX2HDAC1HDAC6PPARG | |
| SCHEMBL2833527 | 0.78 | KMT2A (0.68) | NR1H4EPHX2KMT2AHDAC1HDAC6 | |
| SCHEMBL22059607 | 0.78 | EPHX2 (1.00) | NR1H4EPHX2KMT2AHDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125191-A1 | BENZENE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2009-10-15 | — | — | WO | disclosed |