Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.53 |
| ▸ | PEPD | P12955 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31651948 | 0.85 | P2RY6 (0.56) | P2RY6NPC1MAPTCA1CA2 | |
| SCHEMBL728602 | 0.83 | P2RY6 (0.58) | P2RY6ALDH1A1GAAMAPTKIF11 | |
| SCHEMBL3804765 | 0.81 | RAB9A (0.56) | P2RY6ALDH1A1NPC1GAAMAPT | |
| SCHEMBL25392431 | 0.80 | NPC1 (0.52) | P2RY6NPC1GAACA1CA2 | |
| SCHEMBL3795582 | 0.78 | RAB9A (0.50) | P2RY6NPC1MAPTCA1CA2 | |
| SCHEMBL9921321 | 0.78 | PEPD (0.61) | PEPDALDH1A1NPC1GLAGAA | |
| SCHEMBL5062623 | 0.77 | PEPD (0.80) | PEPDALDH1A1NPC1GLAGAA | |
| SCHEMBL1105876 | 0.76 | PEPD (0.59) | PEPDALDH1A1NPC1GLAGAA | |
| SCHEMBL22883166 | 0.76 | P2RY6 (0.58) | P2RY6ALDH1A1NPC1GAAMAPT | |
| SCHEMBL27897444 | 0.75 | HSD17B10 (0.53) | P2RY6ALDH1A1MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452702-B1 | Functionalized RGD peptidomimetics and their manufacture, and implant having a coating containing such functionalized RGD peptidomimetics | BIOTRONIK AG (CH) | 2015-03-04 | — | — | EP | disclosed |
| EP-2452702-A2 | Functionalized RGD peptidomimetics and their manufacture, and implant having a coating containing such functionalized RGD peptidomimetics | Biotronik AG (CH) | 2012-05-16 | — | — | EP | disclosed |