SCHEMBL4572489

SCHEMBL4572489

CC1(C)c2ccc(-c3ccc4oc5ccccc5c(=O)c4c3)cc2-c2cc(-c3ccc4oc5ccccc5c(=O)c4c3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
MAOA P21397 5/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
PGAM1 P18669 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 6/20 0.49
RAB9A P51151 5/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TTR P02766 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10055372 0.96 CASP3 (0.52) CASP3SENP7SENP6MAOAMAPT
SCHEMBL4572519 0.96 CASP3 (0.52) CASP3SENP7SENP6MAOAMAPT
SCHEMBL12181790 0.96 CASP3 (0.52) CASP3SENP7SENP6MAOAMAPT
SCHEMBL4572528 0.95 CASP3 (0.51) CASP3SENP7SENP6MAOAMAPT
SCHEMBL14701607 0.93 CASP3 (0.49) CASP3SENP7SENP6MAOAMAPT
SCHEMBL12181760 0.92 CASP3 (0.46) CASP3SENP7SENP6MAOAMAPT
SCHEMBL4572483 0.92 HCRTR1 (0.55) CASP3SENP7SENP6MAOAMAPT
SCHEMBL804780 0.88 MAPT (0.49) CASP3SENP7SENP6MAOAMAPT
SCHEMBL26503459 0.88 CASP3 (0.52) CASP3SENP7SENP6MAOAMAPT
SCHEMBL10055192 0.88 CASP3 (0.52) CASP3SENP7SENP6MAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2635561-B1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KK (JP) 2016-12-14 EP disclosed
US-9318712-B2 Xanthone compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-9318712-B2 Xanthone compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-20130214268-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-22 US disclosed
US-20130214268-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-22 US disclosed
WO-2012060234-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-10 WO disclosed