Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574190 | 0.90 | CTSS (0.60) | CTSS | |
| SCHEMBL4574208 | 0.87 | CTSS (0.73) | CTSS | |
| SCHEMBL4085399 | 0.85 | CTSS (0.53) | CTSS | |
| SCHEMBL4572752 | 0.85 | CTSS (0.58) | CTSS | |
| SCHEMBL4572784 | 0.84 | CTSS (0.75) | CTSS | |
| SCHEMBL4084584 | 0.76 | CTSS (0.77) | CTSS | |
| SCHEMBL4090768 | 0.76 | CTSS (0.64) | CTSS | |
| SCHEMBL4093536 | 0.76 | CTSS (0.65) | CTSS | |
| SCHEMBL4534425 | 0.75 | CTSS (0.81) | CTSS | |
| SCHEMBL4528302 | 0.75 | CTSS (0.81) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100635-A1 | 1- [3- (MONOCYCLIC AMINO) PROPYL] - 4, 5, 6, 7-TETRAHYDRO-1H-PYRAZOLO [4, 3-C] -PYRIDINES AS MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |