Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.55 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193529 | 0.87 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL14194368 | 0.80 | HPGD (0.40) | HSP90AA1HSP90AB1TRAP1HPGDCYP1A2 | |
| SCHEMBL14193833 | 0.79 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL4573404 | 0.79 | HSP90AA1 (0.67) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL4572951 | 0.79 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL384744 | 0.75 | HSP90AA1 (0.82) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL15896307 | 0.73 | NAMPT (0.45) | HPGDCYP1A2POLBALDH1A1 | |
| SCHEMBL14194420 | 0.71 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1HPGDCYP1A2 | |
| SCHEMBL14193891 | 0.71 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1HPGDCYP1A2 | |
| SCHEMBL1426117 | 0.71 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053319-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008053319-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-05-08 | — | — | WO | disclosed |