Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 18/20 | 0.67 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.54 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.54 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572951 | 0.98 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL14193833 | 0.84 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL384744 | 0.82 | HSP90AA1 (0.82) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL30474300 | 0.82 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL14193529 | 0.81 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL30474365 | 0.80 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL4573006 | 0.79 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL14194864 | 0.76 | KMT2A (0.41) | TRAP1HSP90B1 | |
| SCHEMBL14193533 | 0.73 | TMEM97 (0.41) | TRAP1HSP90B1 | |
| SCHEMBL20677849 | 0.72 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053319-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008053319-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-05-08 | — | — | WO | disclosed |