Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 7/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 5/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75162 | 0.87 | PDE5A (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL72943 | 0.82 | PDE4A (0.43) | MAOBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8196194 | 0.78 | PDE4B (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL74013 | 0.77 | PDE5A (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL74012 | 0.77 | PDE5A (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL75163 | 0.76 | PDE4A (0.38) | MAOBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5022607 | 0.73 | CYP19A1 (0.48) | MAOBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL73469 | 0.72 | PDE4A (0.41) | MAOBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27822307 | 0.72 | FABP4 (0.54) | PDE4APDE4BPDE4CPDE4DFABP4 | |
| SCHEMBL73468 | 0.71 | PDE5A (0.45) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081282-A3 | PROCESS FOR THE SYNTHESIS OF N9-(3,5-DICHLORO-4-PYRIDYL)-6- DIFLUOROMETHOXYBENZO(4,5)FURO(3,2-C)PYRIDINE-9-CARBOXAMIDE AND SALTS THEREOF | GLENMARK PHARMACEUTICALS SA (CH) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008081282-A2 | PROCESS FOR THE SYNTHESIS OF N9-(3,5-DICHLORO-4-PYRIDYL)-6- DIFLUOROMETHOXYBENZO(4,5)FURO(3,2-C)PYRIDINE-9-CARBOXAMIDE AND SALTS THEREOF | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-07-10 | — | — | WO | disclosed |