Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 17/20 | 0.64 |
| ▸ | NR1H3 | Q13133 | 16/20 | 0.64 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573190 | 1.00 | NR1H2 (0.64) | NR1H2NR1H3GPR119 | |
| SCHEMBL4573084 | 0.88 | NR1H2 (0.57) | NR1H2NR1H3GPR119 | |
| SCHEMBL20139589 | 0.88 | NR1H2 (0.59) | NR1H2NR1H3GPR119 | |
| SCHEMBL4585111 | 0.85 | NR1H2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL18186172 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3GPR119 | |
| SCHEMBL30426972 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3GPR119 | |
| SCHEMBL16824838 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3GPR119 | |
| SCHEMBL31342338 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3GPR119 | |
| SCHEMBL30426904 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3GPR119 | |
| SCHEMBL16378067 | 0.84 | NR1H2 (0.52) | NR1H2NR1H3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |