SCHEMBL4585111 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NR1H2	P55055	11/20	0.48

▸	NR1H3	Q13133	11/20	0.48

▸	CHRM2	P08172	3/20	0.43

▸	CHRM1	P11229	2/20	0.43

▸	HSD11B1	P28845	1/20	0.43

▸	CHRM5	P08912	1/20	0.42

▸	CHRM3	P20309	1/20	0.42

▸	CHRM4	P08173	1/20	0.41

▸	FAAH	O00519	2/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4573024	0.87	NR1H2 (0.42)	NR1H2NR1H3CHRM4FAAH
SCHEMBL4573185	0.85	NR1H2 (0.64)	NR1H2NR1H3
SCHEMBL4573190	0.85	NR1H2 (0.64)	NR1H2NR1H3
SCHEMBL25205050	0.81	CHRM2 (0.45)	CHRM2CHRM1CHRM5CHRM3CHRM4
SCHEMBL25182095	0.81	CHRM2 (0.45)	CHRM2CHRM1CHRM5CHRM3CHRM4
SCHEMBL25205047	0.81	CHRM2 (0.45)	CHRM2CHRM1CHRM5CHRM3CHRM4
SCHEMBL31111518	0.81	CHRM2 (0.57)	CHRM2CHRM1CHRM5CHRM3CHRM4
SCHEMBL4573282	0.81	HSD11B1 (0.45)	HSD11B1CHRM4
SCHEMBL19096975	0.80	CHRM2 (0.43)	NR1H2NR1H3CHRM2CHRM1CHRM5
SCHEMBL17375398	0.80	CHRM2 (0.43)	NR1H2NR1H3CHRM2CHRM1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009001127-A1	CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS	ASTRAZENECA AB (SE)	2008-12-31	—	—	WO	disclosed