Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 4/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470579 | 0.92 | PDE4B (0.51) | PDE4BKDM4DKDM1AUSP30 | |
| SCHEMBL462446 | 0.92 | PDE4B (0.51) | PDE4BKDM4DKDM1AUSP30 | |
| SCHEMBL463402 | 0.84 | PDE4B (0.50) | PDE4BKDM4DKDM1AUSP30FPR1 | |
| SCHEMBL463400 | 0.84 | PDE4B (0.50) | PDE4BKDM4DKDM1AUSP30FPR1 | |
| SCHEMBL463401 | 0.84 | PDE4B (0.50) | PDE4BKDM4DKDM1AUSP30FPR1 | |
| SCHEMBL461989 | 0.76 | KMT2A (0.44) | PDE4BKDM4DKDM1AMAOBFPR1 | |
| SCHEMBL461990 | 0.76 | KMT2A (0.44) | PDE4BKDM4DKDM1AMAOBFPR1 | |
| SCHEMBL147672 | 0.75 | KMT2A (0.48) | — | |
| SCHEMBL147670 | 0.75 | KMT2A (0.48) | — | |
| SCHEMBL147671 | 0.75 | KMT2A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |