Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 3/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463401 | 1.00 | PDE4B (0.50) | PDE4BUSP30KDM4DCYP3A4CYP3A5 | |
| SCHEMBL463402 | 1.00 | PDE4B (0.50) | PDE4BUSP30KDM4DCYP3A4CYP3A5 | |
| SCHEMBL470579 | 0.93 | PDE4B (0.51) | PDE4BUSP30KDM4DCYP3A4CYP3A5 | |
| SCHEMBL462446 | 0.93 | PDE4B (0.51) | PDE4BUSP30KDM4DCYP3A4CYP3A5 | |
| SCHEMBL457321 | 0.84 | PDE4B (0.42) | PDE4BUSP30KDM4DFPR1FPR2 | |
| SCHEMBL470457 | 0.83 | DPP4 (0.57) | PDE4BUSP30CYP3A4CYP3A5STS | |
| SCHEMBL461990 | 0.81 | KMT2A (0.44) | PDE4BKDM4DFPR1FPR2DPP4 | |
| SCHEMBL461989 | 0.81 | KMT2A (0.44) | PDE4BKDM4DFPR1FPR2DPP4 | |
| SCHEMBL462835 | 0.80 | FPR1 (0.46) | KDM4DFPR1FPR2KDM1A | |
| SCHEMBL462837 | 0.80 | FPR1 (0.46) | KDM4DFPR1FPR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |