Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930261 | 0.95 | KMT2A (0.55) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL13642025 | 0.86 | KDM4E (0.50) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL5173975 | 0.85 | KDM4E (0.45) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL1516692 | 0.85 | FBP1 (0.44) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL31053304 | 0.85 | FBP1 (0.44) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL2618834 | 0.83 | KDM4E (0.49) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL4816249 | 0.83 | HPGD (0.57) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL7931144 | 0.82 | HTT (0.54) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL12121221 | 0.81 | KDM4E (0.52) | KDM4EKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL13642366 | 0.81 | KMT2A (0.50) | KDM4EKMT2AALDH1A1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |