Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318007 | 1.00 | HPGD (0.74) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28170795 | 0.87 | MAPT (0.79) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1030477 | 0.85 | GFER (0.83) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12338982 | 0.85 | MAPT (1.00) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3767094 | 0.85 | MAPT (1.00) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2005010 | 0.84 | CA12 (0.81) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3086762 | 0.84 | CA1 (0.66) | MAPTALDH1A1MEN1KMT2ABRD4 | |
| SCHEMBL7211675 | 0.84 | MAPT (0.74) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3081178 | 0.83 | MEN1 (0.65) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5452240 | 0.83 | TMPRSS6 (0.73) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207632-A1 | PROTEIN KINASE INHIBITORS | SUPERGEN, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| WO-2008055233-A1 | PROTEIN KINASE INHIBITORS | SUPERGEN, INC. (US) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207632-A1 | PROTEIN KINASE INHIBITORS | ERBB3, ERBB2, AXL | HPGD 4263/4885MAPT 1472/4885ALDH1A1 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.