SCHEMBL2005010

SCHEMBL2005010

Cc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.81
CA1 P00915 1/20 0.81
CA2 P00918 1/20 0.81
CA9 Q16790 1/20 0.81
ALDH1A1 P00352 9/20 0.76
MAPT P10636 8/20 0.76
LMNA P02545 4/20 0.76
MEN1 O00255 2/20 0.76
KMT2A Q03164 2/20 0.76
TDP1 Q9NUW8 2/20 0.76
ALOX12 P18054 2/20 0.76
GAA P10253 1/20 0.76
MAPK1 P28482 1/20 0.76
GFER P55789 1/20 0.76
MCL1 Q07820 1/20 0.76
HPGD P15428 2/20 0.73
FFAR1 O14842 1/20 0.69
HTT P42858 2/20 0.67
HSD17B10 Q99714 1/20 0.67
TP53 P04637 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9001311 0.94 CA12 (0.72) CA12CA1CA2CA9ALDH1A1
SCHEMBL11705580 0.94 MEN1 (0.86) CA12CA1CA2CA9ALDH1A1
SCHEMBL7565259 0.90 CA1 (0.73) CA12CA1CA2CA9ALDH1A1
SCHEMBL9190472 0.90 CA12 (0.68) CA12CA1CA2CA9ALDH1A1
SCHEMBL930602 0.90 MAPT (0.82) CA12CA1CA2CA9ALDH1A1
SCHEMBL1592808 0.90 MAPT (0.82) CA12CA1CA2CA9ALDH1A1
SCHEMBL11026205 0.90 CA12 (0.68) CA12CA1CA2CA9ALDH1A1
SCHEMBL6831830 0.90 CA12 (0.68) CA12CA1CA2CA9ALDH1A1
SCHEMBL2136408 0.90 CES1 (0.81) CA12CA1CA2CA9ALDH1A1
SCHEMBL94977 0.90 CA12 (0.68) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960435-B2 Anti-cancer agents and androgen inhibition activity compound UNIVERSITY OF MARYLAND, BALTIMORE (US) 2011-06-14 US claimed
US-20100113600-A1 ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND UNIVERSITY OF MARYLAND, BALTIMORE (US) 2010-05-06 US claimed
WO-2008076918-A9 ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND UNIV MARYLAND (US) 2008-08-07 WO claimed
WO-2008076918-A2 ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND UNIVERSITY OF MARYLAND, BALTIMORE (US) 2008-06-26 WO claimed
WO-2006023720-A2 REACTIONS OF ENOLIZABLE A-AMINO ALDEHYDES OR KETONES TO FORM AMINE THE SCRIPPS RESEARCH INSTITUTE (US) 2006-03-02 WO claimed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US claimed
EP-0104353-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1987-10-28 EP claimed
US-4482905-A FLUORAN, BENZENESULFONAMIDE, ACID, BINDER HODOGAYA CHEMICAL CO., LTD. (JP) 1984-11-13 US claimed
EP-0104353-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1984-04-04 EP claimed
US-12427798-B2 Heat-sensitive recording composition NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
CN-116574039-B Polysubstituted aminobenzonitrile compound and preparation method thereof 上海大学 2025-02-28 CN disclosed
US-20250001788-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-01-02 US disclosed
EP-4442468-A1 HEAT-SENSITIVE RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
EP-4442467-A1 THERMAL RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
US-4600797-A NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US disclosed
EP-0082383-B1 PROCESS FOR PREPARING POLYCARBONATES CONTAINING SULFONE ANILIDE END GROUPS BAYER AG (DE) 1985-08-28 EP disclosed
US-4471104-A SELF EXTINGUISHING BAYER AKTIENGESELLSCHAFT (DE) 1984-09-11 US disclosed
EP-0049711-B1 PROCESS FOR THE PRODUCTION OF NITRO-AMINO-BENZENES BAYER AG (DE) 1984-02-29 EP disclosed
EP-0082383-A1 Process for preparing polycarbonates containing sulfone anilide end groups BAYER AG (DE) 1983-06-29 EP disclosed
EP-0049711-A1 Process for the production of nitro-amino-benzenes BAYER AG (DE) 1982-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113600-A1 ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND AR, HTR3D, NR5A1 CA12 2133/4885CA1 2862/4885CA2 2614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.