SCHEMBL457390

SCHEMBL457390

C=CC[CH]CCCCCC

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.64
ALDH1A1 P00352 1/20 0.48
THRB P10828 1/20 0.40
FAAH O00519 2/20 0.39
TRPV1 Q8NER1 2/20 0.39
DNM1 Q05193 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL174671 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL21523245 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL1817557 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL174965 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL21523251 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL21523255 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL11040758 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL6338550 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL21523244 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL174833 1.00 TSHR (0.64) TSHRALDH1A1THRBFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974854-B Phenol alkenyl phthalide pyrazolone compound, and preparation method and application thereof 四川大学 2024-04-19 CN claimed
CN-118119589-A Phenol aromatic compound precursor 奇华顿股份有限公司 2024-05-31 CN disclosed
EP-4222180-B1 BIS(HETEROCYCLIC-OLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-04-10 EP disclosed
WO-2024017372-A1 INDOLONE DERIVATIVE AND USE THEREOF 成都百裕制药股份有限公司 2024-01-25 WO disclosed
WO-2024012541-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF 百奥泰生物制药股份有限公司 2024-01-18 WO disclosed
WO-2024012536-A1 ANTI-NECTIN-4 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF 百奥泰生物制药股份有限公司 2024-01-18 WO disclosed
WO-2024001115-A1 KAURANE TETRACYCLIC DITERPENOID DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 中国药科大学 2024-01-04 WO disclosed
WO-2023237103-A1 PYRROLIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF IN MEDICINE 成都百裕制药股份有限公司 2023-12-14 WO disclosed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US disclosed
US-11732063-B2 Lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
EP-2364773-A1 Improved microcapsules and their manufacture Follmann & Co. Gesellschaft für Chemie-Werkstoffe und -Verfahrenstechnik mbH & Co. KG (DE) 2011-09-14 EP disclosed
WO-2010102830-A2 IMPROVED MICROCAPSULES, AND PRODUCTION THEREOF FOLLMANN & CO. GESELLSCHAFT FÜR CHEMIE-WERKSTOFFE UND VERFAHRENSTECHNIK MBH & CO. KG (DE) 2010-09-16 WO disclosed
US-6437123-B1 NEMATIC DISCOTIC LIQUID CRYSTAL PHASE, A COLUMNAR LIQUID CRYSTAL PHASE AND/OR A COLUMNAR CRYSTALLINE PHASE; ELECTRON-DEFICIENT CENTRAL UNIT THAT FAVOURS TRANSPORT OF ELECTRONS, ELECTROLUMINESCENT SHARP KABUSHIKI KAISHA (JP) 2002-08-20 US disclosed
EP-0713867-B1 Lubricating oil compositions SHELL INT RESEARCH (NL) 2000-02-16 EP disclosed
EP-0713867-A1 Lubricating oil compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1996-05-29 EP disclosed
WO-1993023398-A1 SUBSTITUTED PYRIDO[1,2-A]PYRIMIDINONE DERIVATIVES AS FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-11-25 WO disclosed
EP-0000746-B1 ORGANO TIN COMPOUNDS, THEIR PREPARATION AND THEIR APPLICATION HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-28 EP disclosed
US-4237043-A STABILIZERS FOR CHLOROPOLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-02 US disclosed
EP-0011280-A1 Process for the preparation of organotin trihalides and their application HOECHST AKTIENGESELLSCHAFT (DE) 1980-05-28 EP disclosed
EP-0000746-A1 Organo tin compounds, their preparation and their application HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11732063-B2 Lewis base catalysts and methods thereof TEC, ALOX12, ELL TSHR 3939/4885ALDH1A1 2743/4885THRB 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.