Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1924194 | 0.93 | GPR119 (0.54) | GPR119KDM4ENPC1RAB9A | |
| SCHEMBL1103984 | 0.87 | GPR119 (0.48) | GPR119KDM4ENPC1RAB9A | |
| SCHEMBL2247872 | 0.84 | GPR119 (0.48) | GPR119KDM4ENPC1RAB9A | |
| SCHEMBL15109948 | 0.81 | GPR119 (0.44) | GPR119KDM4ENPC1RAB9A | |
| SCHEMBL17712603 | 0.80 | GPR119 (0.49) | GPR119KDM4ENPC1RAB9A | |
| SCHEMBL1004837 | 0.79 | GPR119 (0.53) | GPR119KDM4ENPC1RAB9A | |
| SCHEMBL2250812 | 0.79 | GPR119 (0.45) | GPR119 | |
| SCHEMBL23226149 | 0.79 | GPR119 (0.43) | GPR119 | |
| SCHEMBL12356451 | 0.77 | GPR119 (0.53) | GPR119KDM4ENPC1RAB9A | |
| SCHEMBL19438238 | 0.77 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |