SCHEMBL4574028

SCHEMBL4574028

CC(C)(C)OC(=O)NC(CO)C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA7 P43166 1/20 0.53
CYP2D6 P10635 1/20 0.47
CTSK P43235 11/20 0.45
CTSS P25774 6/20 0.45
TDP1 Q9NUW8 1/20 0.42
CTSL P07711 2/20 0.40
CTSB P07858 2/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
APLNR P35414 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56783 1.00 CA1 (0.53) CA1CA2CA7CYP2D6CTSK
SCHEMBL56671 1.00 CA1 (0.53) CA1CA2CA7CYP2D6CTSK
SCHEMBL3685399 0.86 CA1 (0.47) CA1CA2CA7CYP2D6CTSK
SCHEMBL23925023 0.86 CA1 (0.47) CA1CA2CA7CYP2D6CTSK
SCHEMBL14496991 0.86 CA1 (0.47) CA1CA2CA7CYP2D6CTSK
SCHEMBL1352540 0.85 CA1 (0.46) CA1CA2CA7CYP2D6CTSK
SCHEMBL31255051 0.85 CA1 (0.46) CA1CA2CA7CYP2D6CTSK
SCHEMBL1692753 0.85 CA1 (0.46) CA1CA2CA7CYP2D6CTSK
SCHEMBL22362992 0.85 CA1 (0.46) CA1CA2CA7CYP2D6CTSK
SCHEMBL30365028 0.85 CA1 (0.46) CA1CA2CA7CYP2D6CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340554-A1 5-Amino-1H-Pyrrolo[3,2-b]Pyridine-2-Carboxamide Derivatives as MTA-Cooperative Inhibitors of PRMT5 BEONE MEDICINES I GMBH (CH) 2025-11-06 US disclosed
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed
CN-115279767-B Tetracyclic compounds as inhibitors of hepatitis b surface antigen 正大天晴药业集团股份有限公司 2024-12-06 CN disclosed
CN-113166143-B N-1 branched alkyl ether substituted imidazo [4,5-c ] quinoline compounds, compositions and methods 舒万诺知识产权公司 2024-06-04 CN disclosed
EP-3887369-B1 N-1 BRANCHED ALKYL ETHER SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-05-08 EP disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed
CN-110831942-B Fused indazolopyridinone compounds as antiviral agents 诺华股份有限公司 2023-04-04 CN disclosed
CN-115279767-A Tetracyclic compounds as inhibitors of hepatitis B surface antigen 正大天晴药业集团股份有限公司 2022-11-01 CN disclosed
CN-110831942-A Fused indazolopyridinone compounds as antiviral agents 诺华股份有限公司 2020-02-21 CN disclosed
EP-3162438-A1 POLYMER SUPPORTED VICINAL DIAMINES AND THEIR USE AS CATALYST IN THE HAJOS-PARRISH-ENDER-SAUSER-WIECHERT AND ROBINSON ANNULATION REACTIONS Fundació Institut Català d'Investigació Química (ES) 2017-05-03 EP disclosed
WO-2008070358-A2 N-CYCLOPROPYL-HYDROXYPROLINE-BASED TRIPEPTIDIC HEPATITIS C SERINE PROTEASE INHIBITORS CONTAINING AN ISOINDOLE, PYRROLOPYRIDINE, PYRROLOPYRIMIDINE OR PYRROLOPYRAZINE HETEROCYCLE IN THE SIDE CHAIN PHENOMIX CORPORATION (US) 2008-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340554-A1 5-Amino-1H-Pyrrolo[3,2-b]Pyridine-2-Carboxamide Derivatives as MTA-Cooperative Inhibitors of PRMT5 PRMT5, PRMT1, PRMT3 CA1 4280/4885CA2 3582/4885CA7 4475/4885
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD CA1 548/4885CA2 597/4885CA7 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.