Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP1 | P09455 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574575 | 0.99 | RBP1 (0.46) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4574182 | 0.97 | ALOX5AP (0.45) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8223460 | 0.94 | RBP1 (0.40) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4574617 | 0.86 | KMT2A (0.62) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4574830 | 0.86 | KMT2A (0.47) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8212341 | 0.85 | KMT2A (0.46) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4574980 | 0.85 | KMT2A (0.61) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4574917 | 0.84 | KMT2A (0.46) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4574604 | 0.81 | KMT2A (0.42) | RBP1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL4575063 | 0.80 | ALOX5AP (0.43) | RBP1KMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |