Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | RBP1 | P09455 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574617 | 0.99 | KMT2A (0.62) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL4575272 | 0.93 | KMT2A (0.55) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL8212341 | 0.86 | KMT2A (0.46) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL4574575 | 0.86 | RBP1 (0.46) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL4574830 | 0.85 | KMT2A (0.47) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL4574107 | 0.85 | RBP1 (0.46) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL4574917 | 0.83 | KMT2A (0.46) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL4574182 | 0.82 | ALOX5AP (0.45) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL4574604 | 0.80 | KMT2A (0.42) | KMT2AMEN1LMNARBP1ALDH1A1 | |
| SCHEMBL4575063 | 0.79 | ALOX5AP (0.43) | KMT2AMEN1LMNARBP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |