Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38192 | 0.97 | IDO1 (0.46) | IDO1MAPTLMNANPC1HTT | |
| Ammonia Solution, Strong SCHEMBL28307654 | 0.95 | IDO1 (0.44) | IDO1MAPTLMNANPC1HTT | |
| SCHEMBL23578319 | 0.91 | MAOB (0.47) | IDO1MAPTLMNANPC1HTT | |
| SCHEMBL8993309 | 0.91 | MAPT (0.41) | IDO1MAPTLMNANPC1HTT | |
| SCHEMBL2154504 | 0.84 | KMT2A (0.47) | MAPTLMNANPC1HTTCYP2A6 | |
| Propionaldehyde SCHEMBL27180807 | 0.82 | MAPT (0.40) | IDO1MAPTLMNANPC1HTT | |
| SCHEMBL1368028 | 0.78 | IDO1 (0.40) | IDO1MAPTLMNANPC1HTT | |
| SCHEMBL14999782 | 0.78 | ALDH1A1 (0.47) | MAPTLMNANPC1HTTKMT2A | |
| SCHEMBL4117959 | 0.78 | NPC1 (0.74) | MAPTLMNANPC1HTTKMT2A | |
| SCHEMBL2939551 | 0.77 | CA1 (0.41) | MAPTLMNANPC1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |