SCHEMBL4574671

SCHEMBL4574671

CCOc1ccc(CC(CN(CCN(CCC(=O)O)CC(=O)O)CC(=O)O)N(CCC(=O)O)CC(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAOB P27338 4/20 0.41
ACACB O00763 9/20 0.40
LTA4H P09960 2/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1943044 0.94 MAOB (0.41) LMNAL3MBTL1MAOBACACBFFAR1
Caloxetic Acid Free Base SCHEMBL8412091 0.90 MAOB (0.43) MAOBACACBALOX5
Caloxetic Acid Free Base SCHEMBL92689 0.90 MAOB (0.43) MAOBACACBALOX5
SCHEMBL1197902 0.89 MAOB (0.43) LMNAL3MBTL1MAOBACACBLTA4H
Caloxetic Acid Free Base SCHEMBL29375456 0.89 MAOB (0.42) MAOBACACBALOX5
Caloxetic Acid Free Base SCHEMBL19667947 0.89 MAOB (0.42) MAOBACACBALOX5
SCHEMBL8672662 0.89 MAOB (0.42) MAOBACACBALOX5
Caloxetic Acid Free Base SCHEMBL19667948 0.89 MAOB (0.42) MAOBACACBALOX5
SCHEMBL21919160 0.88 MAOB (0.40) L3MBTL1MAOBACACBALOX5
SCHEMBL21919169 0.88 MAOB (0.42) MAOBACACBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501552-B1 MR-SIGNAL EMITTING COATINGS WISCONSIN ALUMNI RES FOUND (US) 2008-05-28 EP claimed
EP-1785146-A2 Mr-signal emitting coatings WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-05-16 EP claimed
US-6896874-B2 Providing a coating on the medical device in which a paramagnetic-metal ion/chelate complex is encapsulated by a hydrogel, a chelate being linked to a functional group, and the functional group being an amine group WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2005-05-24 US claimed
EP-1501552-A1 MR-SIGNAL EMITTING COATINGS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2005-02-02 EP claimed
US-20040253292-A1 MR-signal emitting coatings WISCONSIN ALUMNI RESEARCH FOUNDATION 2004-12-16 US claimed
WO-2004093921-A1 MR-SIGNAL EMITTING COATINGS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2004-11-04 WO claimed
WO-2003094975-A1 MR-SIGNAL EMITTING COATINGS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2003-11-20 WO claimed
US-20030099764-A1 Providing a coating on the medical device in which a paramagnetic-metal ion/chelate complex is encapsulated by a hydrogel, a chelate being linked to a functional group, and the functional group being an amine group WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-05-29 US claimed
US-8532742-B2 System and method for simultaneous 3DPR device tracking and imaging under MR-guidance for therapeutic endovascular interventions WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-09-10 US disclosed
US-8457712-B2 Multi-mode medical device system and methods of manufacturing and using same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-06-04 US disclosed
US-8412306-B2 Voltage standing wave suppression for MR-guided therapeutic interventions WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-04-02 US disclosed
EP-1971873-A1 INTERVENTIONAL MEDICAL DEVICE ALLOWING MR IMAGING AND TRACKING WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-09-24 EP disclosed
WO-2008106201-A1 VOLTAGE STANDING WAVE SUPPRESSION FOR MR-GUIDED THERAPEUTIC INTERVENTIONS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-09-04 WO disclosed
WO-2008106212-A1 SYSTEM AND METHOD OF PERFORMING THERAPEUTIC ENDOVASCULAR INTERVENTIONS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-09-04 WO disclosed
US-20070156042-A1 Medical device system and method for tracking and visualizing a medical device system under MR guidance NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-07-05 US disclosed
EP-1785146-A2 Mr-signal emitting coatings WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-05-16 EP disclosed
US-6896874-B2 Providing a coating on the medical device in which a paramagnetic-metal ion/chelate complex is encapsulated by a hydrogel, a chelate being linked to a functional group, and the functional group being an amine group WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2005-05-24 US disclosed
US-20040253292-A1 MR-signal emitting coatings WISCONSIN ALUMNI RESEARCH FOUNDATION 2004-12-16 US disclosed
WO-2004093921-A1 MR-SIGNAL EMITTING COATINGS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2004-11-04 WO disclosed
US-20030099764-A1 Providing a coating on the medical device in which a paramagnetic-metal ion/chelate complex is encapsulated by a hydrogel, a chelate being linked to a functional group, and the functional group being an amine group WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-05-29 US disclosed