Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 9/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574671 | 0.89 | LMNA (0.41) | MAOBLMNAL3MBTL1ACACBLTA4H | |
| SCHEMBL1198247 | 0.87 | MAOB (0.56) | MAOBLTA4HFFAR1FFAR4ALOX5 | |
| SCHEMBL1943044 | 0.86 | MAOB (0.41) | MAOBLMNAL3MBTL1ACACBFFAR1 | |
| SCHEMBL8672662 | 0.84 | MAOB (0.42) | MAOBALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL1197225 | 0.83 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5133619 | 0.82 | MAOB (0.50) | MAOBACACB | |
| Caloxetic Acid Free Base SCHEMBL8412091 | 0.81 | MAOB (0.43) | MAOBALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL8338898 | 0.81 | ALDH1A1 (0.43) | MAOBALDH1A1POLBCYP2C9CYP2C19 | |
| Caloxetic Acid Free Base SCHEMBL92689 | 0.81 | MAOB (0.43) | MAOBALDH1A1POLBCYP2C9CYP2C19 | |
| Caloxetic Acid Free Base SCHEMBL19667948 | 0.80 | MAOB (0.42) | MAOBALDH1A1POLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064026-A1 | Lipophilic metal complexes for necrosis and infarction imaging | SCHERING AG (DE) | 2003-04-03 | — | — | US | claimed |
| US-6495118-B1 | Lipophilic metal complexes for necrosis and infarction imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | claimed |
| US-8741262-B2 | Targeted radiotherapy | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2014-06-03 | — | — | US | disclosed |
| EP-2219683-B1 | TARGETED RADIOTHERAPY | UNIV LEUVEN KATH (BE) | 2012-05-30 | — | — | EP | disclosed |
| US-20110038795-A1 | TARGETED RADIOTHERAPY | KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R&D (BE) | 2011-02-17 | — | — | US | disclosed |
| EP-2219683-A2 | TARGETED RADIOTHERAPY | Katholieke Universiteit Leuven (BE) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009067767-A2 | TARGETED RADIOTHERAPY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2009-06-04 | — | — | WO | disclosed |
| US-20030064026-A1 | Lipophilic metal complexes for necrosis and infarction imaging | SCHERING AG (DE) | 2003-04-03 | — | — | US | disclosed |